Historical Disease Awareness

    "No, I said Mu"

    Get to know mu-receptors and opioid-induced constipation

    Opioids play an important role in chronic pain relief by binding to mu-receptors in the brain and blocking pain signals. But they also bind to mu-receptors in the bowel. That's why patients taking opioids for chronic pain can develop opioid-induced constipation and why AstraZeneca wanted to help HCPs understand the connection.